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Spice Up Your Life, Not Your Food: Study Links Inflammatory Diets and Excess Salt to Soaring Diabetes Risk

Written by Andrew Le, MD

UpdatedMarch 20, 2024

New Research Reveals Link Between Diet, Salt Consumption, and Type 2 Diabetes Risk

A groundbreaking study has just highlighted the significant connection between the food we eat, how much salt we sprinkle on it, and our chances of developing type 2 diabetes. This serious health condition affects millions worldwide, and the insights from this research could have vital implications for public health strategies aimed at combating diabetes.

The research was published in the medical journal "Diabetes Obesity Metabolism" and embarked on the ambitious task of uncovering the relationships between a proinflammatory diet, habitual salt intake, and the onset of type 2 diabetes.

The Science Behind the Study

Diabetes has been an increasing concern across the globe, with projections suggesting 700 million people could be affected by 2045. Since diet is a critical factor we can control to combat this disease, the study zeroed in on how the foods that promote inflammation and how much salt we consume can play a role in the risk of developing diabetes.

This research was a prospective cohort study conducted with over 171,000 participants from the UK Biobank. To provide accurate and reliable data, these individuals had no history of diabetes at the study's start and completed at least one 24-hour dietary questionnaire.

Scientists then kept track of the participants until March 2023, noting new cases of type 2 diabetes. They used a specially designed tool, the Energy-adjusted Diet Inflammatory Index (E-DII), to gauge each participant's diet's inflammatory potential. This was based on an analysis of 28 food parameters. Additionally, the habitual salt intake was determined through the self-reported frequency of adding salt to foods.

The researchers analyzed the data using the statistical method known as the Cox proportional hazard regression model to determine if and how these dietary aspects affected the development of type 2 diabetes.

What The Numbers Showed

After following the participants for a median of 13.5 years, 6,216 individuals were newly diagnosed with type 2 diabetes. The study revealed that those with a high E-DII score, which signals a proinflammatory diet, had an 18% increased risk of developing diabetes compared with those with diets considered anti-inflammatory. This association appeared to be linear even after accounting for other potential influencing factors.

The findings became even more concerning when factoring in salt intake. Participants who had diets high in inflammatory potential and who consistently added salt to their food were at the highest risk of developing diabetes, showing a 60% heightened risk (with a 95% confidence interval from 32% to 94% higher risk).

What Does This Mean Going Forward?

The results of this research support the notion that diet plays a crucial role in the risk of type 2 diabetes. More specifically, diets that tend to promote inflammation and high salt intake are linked to an increased chance of developing the disease.

As a result, the study's conclusion encourages public health initiatives focusing on promoting an anti-inflammatory diet and reducing salt intake. This twofold approach could be an effective strategy for preventing the onset of type 2 diabetes, thus helping to stem the tide of an escalating global health crisis.

In essence, the choices we make at the dining table—like reaching for the salt shaker or picking proinflammatory foods—could have long-term implications on our health, particularly concerning type 2 diabetes. This research serves as a reminder of the power of prevention and the critical role of a balanced, mindful diet in maintaining our health.

What Are Proinflammatory Foods?

Put simply, proinflammatory foods are those that can trigger or worsen inflammation throughout the body. They can include processed foods, those high in refined sugars and unhealthy fats, and certain meats. On the flip side, anti-inflammatory foods are ones that help to reduce inflammation and could include fruits, vegetables, nuts, and whole grains.

And Salt?

While salt is necessary for normal body functions, too much salt can cause or exacerbate inflammation and other health issues, including high blood pressure. It's a common ingredient we often overlook, but this study brings it into focus as an important dietary factor to control.

A Step Toward a Healthier Future

The insights gained from this research have profound implications, not only for people at risk of developing diabetes but also for anyone looking to maintain a healthy lifestyle. Embracing an anti-inflammatory diet and keeping an eye on our salt intake could be simple yet effective steps toward a healthier future.

However, it is also important to recognize that modifying diet is just one part of the puzzle. Regular physical activity, maintaining a healthy weight, and other lifestyle choices also play a crucial role in preventing chronic diseases like type 2 diabetes.

A Call to Action

Researchers and health officials alike hope that these findings will resonate with individuals and communities worldwide. It's a call to action for everyone to reassess our diet and lifestyle choices for the sake of our long-term health.

By understanding the powerful influence of diet and incorporating more anti-inflammatory foods into our meals while minimizing salt intake, we can take proactive steps towards not only reducing the risk of diabetes but enhancing our overall well-being.

References

Shen W, Cai L, Wang B, et al. Associations of a proinflammatory diet, habitual salt intake, and the onset of type 2 diabetes: A prospective cohort study from the UK Biobank. Diabetes Obes Metab. 2024; 1-9. doi:10.1111/dom.15517